Center for
Excessive
Sweating

Center for Excessive Sweating
5225 Sheridan Drive
Williamsville, NY 14221
(716) 839-3638

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The Center for Excessive Sweating and the Buffalo Sabres

National Center of Excellence for Hyperhidrosis Treatment

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How Does Aluminum Chloride Stop Excessive Sweating (Hyperhidrosis) ?

By: Hratch Karamanoukian, MD and Raffy Karamanoukian, MD

July 18, 2008

How Does Aluminum Chloride Stop Excessive Sweating (Hyperhidrosis) ?

Aluminum chloride solutions work by the 'plug theory' - first proposed by Reller and Luedders - it utilizes the expression of eccrine sweat onto the surface of the skin into which the solid antiperspirant salts, typically an aluminium chlorohydrate dissolve. The resultant acidic 'solution' then diffuses with time into the sweat glands, where it hydrolyses in more alkaline sweat and forms an amorphous metal hydroxide agglomerate that physically plugs the ducts some 20-100 micrometers into the glands. This effectively plugs the sweat aglands.

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For more information about hyperhidrosis (excessive sweating) , as well as surgical and non-surgical hyperhidrosis treatment options, contact Dr. Karamanoukian at The Center for Excessive Sweating, a National Center of Excellence for Hyperhidrosis Treatment by email or by phone at (716) 839-3638.



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