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Williamsville, NY 14221
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Does air pollution alter blood coagulation and cause cardiovascular disease?

By: Hratch Karamannoukian MD and Raffy Karamanoukian MD

July 24, 2008

Consistent evidence has indicated that air pollution increases the risk of cardiovascular diseases. The underlying mechanisms linking air pollutants to increased cardiovascular risk have not been elucidated.


A seminal study published in 2007 by a research group at Harvard “investigated the association between the pollution levels and changes in such global coagulation tests as the prothrombin time (PT) and the activated partial thromboplastin time (APTT)” to see if this would be a clue as to why air pollution increased the risk of developing cardiovascular disorders.


The investigation by Dr. Baccarelli from the Department of Environmental Health, Harvard School of Public Health, Boston, MA shows that air pollution is associated with changes in the global coagulation function, suggesting a tendency towards hypercoagulability after short-term exposure to air pollution. The authors concluded further that “whether these changes contribute to trigger cardiovascular events remains to be established”.


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For more information about hyperhidrosis (excessive sweating) , as well as surgical and non-surgical hyperhidrosis treatment options, contact Dr. Karamanoukian at The Center for Excessive Sweating, a National Center of Excellence for Hyperhidrosis Treatment by email or by phone at (716) 839-3638.

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