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Center for Excessive Sweating
5225 Sheridan Drive
Williamsville, NY 14221
(716) 839-3638

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National Center of Excellence for Hyperhidrosis Treatment


Botox Injected for Palmar Hyperhidrosis Can Cause Severe Atrophy of the Hand Muscles

By: Hratch Karamanoukian, MD and Raffy Karamanoukian, MD

August 2, 2008

Botox, Palmar Hyperhidrosis and Atrophy of Hand Muscles

An article published in the Journal of Plastic Reconstructive Aesthetic Surgery (June 2008) reports a case of an individual with hyperhidrosis of the palms who had Botulinum toxin type A (Botox) injected – this treated the hyperhidrosis but was associated with the development of severe atrophy of the intrinsic muscles of the hands. Although hyperhidrosis of the hands has been shown to be effectively treated with Botox injections, such atrophy of the intrinsic muscles of the hand have not been reported to date.  
For more information about ETS, sympathectomy for palmar hyperhidrosis, contact Dr. Karamanoukian at
or call 716-839-3638


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For more information about hyperhidrosis (excessive sweating) , as well as surgical and non-surgical hyperhidrosis treatment options, contact Dr. Karamanoukian at The Center for Excessive Sweating, a National Center of Excellence for Hyperhidrosis Treatment by email or by phone at (716) 839-3638.

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