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Center for Excessive Sweating
5225 Sheridan Drive
Williamsville, NY 14221
(716) 839-3638

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The Center for Excessive Sweating and the Buffalo Sabres

National Center of Excellence for Hyperhidrosis Treatment


Cardiac Effects of Endoscopic Thoracic Sympathectomy (ETS)

By: Hratch Karamanoukian, MD

August 13, 2008


  • A study was done to determine the effect of Endoscopic Thoracic Sympathectomy (ETS) on physiological responses at rest and during exercise in ten healthy patients by researchers at the Department of Life Sciences, Zinman College, Wingate Institute, Netanya, Israel. The study published in the European Journal of Applied Physiology was authored by Dr. Inbar and colleagues and studied patients who had ETS for axillary and/or palmar hyperhidrosis.

  • Physiological variables were recorded at rest and during sub-maximal (steady-state) and maximal treadmill exercise immediately prior to and 70 days after bilateral ETS.


  • Heart rate was significantly reduced at rest (14%), at sub-maximal exercise (12.3%), and at peak exercise (5.7%), together with a significant increase in oxygen pulse (11.8, 12.7, and 7.8%, respectively).


  • The authors concluded from this study that “thoracic-sympathetic denervation affects the heart, sweating, and circulation of the respective denervated region but does not affect exercise performance or mechanical/physiologic efficiency, despite a significant reduction in heart rate (both at rest and during exercise)”.



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For more information about hyperhidrosis (excessive sweating) , as well as surgical and non-surgical hyperhidrosis treatment options, contact Dr. Karamanoukian at The Center for Excessive Sweating, a National Center of Excellence for Hyperhidrosis Treatment by email or by phone at (716) 839-3638.

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